Published in International Journal JDSCT: MFCI’s Novel Triazine UV Filters’ Safety Profile Validated By Experimental Data

Recently, the research achievement titled "Assessment of the potential genotoxicity and phototoxicity of triazine UV filters", jointly conducted by MFCI CO., LTD and Zhigang Wang's team at Hubei Polytechnic University, has been officially published in the international journal Journal of Dermatologic Science and Cosmetic Technology (JDSCT).

The study systematically verified that MFCI's core products-Ethylhexyl Triazone (EHT, trade name: Mfsorb^® 507) and Diethylhexyl Butamido Triazone (HEB, trade name: Mfsorb^® 513)-pose no genotoxic or phototoxic risks. Experimental results demonstrated that neither EHT nor HEB induced gene mutations, chromosomal structural abnormalities, or significant increases in micronucleus frequency. In vitro 3T3 cell phototoxicity tests revealed a Photo Irritation Factor (PIF) < 2 and Mean Photo Effect (MPE) < 0.1, well below safety thresholds. Additionally, animal skin phototoxicity tests showed no erythema or edema reactions upon UV irradiation.

This research provides internationally authoritative scientific evidence for the safe application of the Mfsorb^® series in sunscreen cosmetics. It not only facilitates clients' compliance with regulatory requirements in the EU, Japan, and South Korea but also guides future R&D toward UV filters with lower skin permeability and enhanced safety profiles.

The publication of this paper underscores MFCI's leadership and innovation capabilities in the UV absorber sector, further strengthening its global presence in the cosmetic ingredients market. Moving forward, MFCI remains committed to advancing the innovation and widespread adoption of UV filters, contributing to both human health and cosmetic science.